Indeed, Spring doesn't make testing harder...it makes it easier.
When you use dependency injection and inject as interfaces, you make it so simple to simply create a mock implementation of those interfaces and wire them into the class you're testing. Keep in mind that in a unit test, your test is doing the wiring of the mocks...not Spring. Spring shouldn't be involved in a unit-testing.
For integration testing Spring can get involved...and for the most part you can (and should) use the same Spring configuration that you use in the production runtime. If there are some things you do *not* want to be real and need to be mocked during the integration test, then let Spring wire them. That's where breaking the context into multiple XML files comes in handy...you can use most of the same XML configs for most of the application...and substitute a test configuration for the parts that need to be mocked up.
One last thought...I said that interfaces make it easy to do mocking...that's true and there are a lot of other good reasons to use interfaces. But using a mocking framework such as
Mockito makes it possible to mock out concrete classes. So the interface-oriented approach isn't strictly necessary for mocking...but it's still a good idea in many cases.