I personally do not think so, but then I am not your employer
2.5 years and one year sound stable enough. You do not convey the impression of being a job hopper.
I would suggest being honest and up front during the interview, regarding the reason for a job change. I have observed many companies respect and encourage family values. Switching jobs because of family issues would be seen as a positive point for such kind of companies.
On the flip side, it would also (probably) mean you would not be available for work outside your home town. If your prospective employer is the kind where the employees need to be on the client site for development, then it might work against you.
I would suggest, be upfront and make sure you discuss and clarify this point during the interview.
Best of luck on your job hunt