Yup, Chris has got this one. There's no right or wrong answer, it's simply gauging how you would react and your methods of problem solving.
For the XML one for example, my answer would be something like this: Check the logs. Search for "Exception" and "error", and have a poke around to see what's in there. Hopefully you've got some better support tooling (maybe splunk/geneos etc) which can show what's going on. Next, try the connection myself. If I can use a
test client I can check to see if everything works as expected. If it does then it's probably a network/proxy issue assuming that I'm probably on the same network as the server at work. Depending on the demands of the application (are we losing millions of pounds?) I'd probably do a rolling restart, because as all developers know turning it off and on again normally works ;).
When actually answering this question though it would be an interactive discussion so this would probably get fleshed out a bit as we went through.